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Effects of chemical modification on the potency, serum stability, and immunostimulatory properties of short shRNAs

Small hairpin RNAs (shRNAs) with 19-base-pair, or shorter, stems (short shRNAs [sshRNAs]) have been found to constitute a class whose mechanism of action appears to be distinct from that of small interfering RNAs (siRNAs) or longer shRNAs. These sshRNAs can be as active as canonical siRNAs or longer...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Ge, Qing, Dallas, Anne, Ilves, Heini, Shorenstein, Joshua, Behlke, Mark A., Johnston, Brian H.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Cold Spring Harbor Laboratory Press 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2802022/
https://ncbi.nlm.nih.gov/pubmed/19948766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1901810
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