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Minimizing variables among hairpin-based RNAi vectors reveals the potency of shRNAs

RNA interference (RNAi) is a cellular process regulating gene expression and participating in innate defense in many organisms. RNAi has also been utilized as a tool to query gene function and is being developed as a therapeutic strategy for several diseases. Synthetic small interfering (siRNAs) or...

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Detalhes bibliográficos
Main Authors: Boudreau, Ryan L., Monteys, Alex Mas, Davidson, Beverly L.
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2525944/
https://ncbi.nlm.nih.gov/pubmed/18697922
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.1062908
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