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Short hairpin RNAs (shRNAs) induce sequence-specific silencing in mammalian cells
RNA interference (RNAi) was first recognized in Caenorhabditis elegans as a biological response to exogenous double-stranded RNA (dsRNA), which induces sequence-specific gene silencing. RNAi represents a conserved regulatory motif, which is present in a wide range of eukaryotic organisms. Recently,...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC152352/ https://ncbi.nlm.nih.gov/pubmed/11959843 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.981002 |
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