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A DNA vector-based RNAi technology to suppress gene expression in mammalian cells
Double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful reverse genetic tool to silence gene expression in multiple organisms including plants, Caenorhabditis elegans, and Drosophila. The discovery that synthetic double-stranded, 21-nt small interfering RNA triggers gene-...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2002
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC122801/ https://ncbi.nlm.nih.gov/pubmed/11960009 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.082117599 |
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