A DNA vector-based RNAi technology to suppress gene expression in mammalian cells

Double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful reverse genetic tool to silence gene expression in multiple organisms including plants, Caenorhabditis elegans, and Drosophila. The discovery that synthetic double-stranded, 21-nt small interfering RNA triggers gene-...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sui, Guangchao, Soohoo, Christina, Affar, El Bachir, Gay, Frédérique, Shi, Yujiang, Forrester, William C., Shi, Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 2002
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC122801/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11960009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.082117599
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