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N Terminus of CtIP Is Critical for Homologous Recombination-mediated Double-strand Break Repair

DNA double-strand breaks (DSBs) represent one of the most lethal types of DNA damage cells encounter. CtIP (also known as RBBP8) acts together with the MRN (MRE11-RAD50-NBS1) complex to promote DNA end resection and the generation of single-stranded DNA, which is critically important for homologous...

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Detaylı Bibliyografya
Asıl Yazarlar: Yuan, Jingsong, Chen, Junjie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2009
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2797245/
https://ncbi.nlm.nih.gov/pubmed/19759395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023424
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