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N Terminus of CtIP Is Critical for Homologous Recombination-mediated Double-strand Break Repair
DNA double-strand breaks (DSBs) represent one of the most lethal types of DNA damage cells encounter. CtIP (also known as RBBP8) acts together with the MRN (MRE11-RAD50-NBS1) complex to promote DNA end resection and the generation of single-stranded DNA, which is critically important for homologous...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Biochemistry and Molecular Biology
2009
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797245/ https://ncbi.nlm.nih.gov/pubmed/19759395 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.023424 |
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