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CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks
The pleiotropic CCCTC-binding factor (CTCF) plays a role in homologous recombination (HR) repair of DNA double-strand breaks (DSBs). However, the precise mechanistic role of CTCF in HR remains largely unclear. Here, we show that CTCF engages in DNA end resection, which is the initial, crucial step i...
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| Published in: | Nucleic Acids Res |
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| Main Authors: | , , , , , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2019
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6753481/ https://ncbi.nlm.nih.gov/pubmed/31340001 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz639 |
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