CTCF cooperates with CtIP to drive homologous recombination repair of double-strand breaks

The pleiotropic CCCTC-binding factor (CTCF) plays a role in homologous recombination (HR) repair of DNA double-strand breaks (DSBs). However, the precise mechanistic role of CTCF in HR remains largely unclear. Here, we show that CTCF engages in DNA end resection, which is the initial, crucial step i...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Hwang, Soon Young, Kang, Mi Ae, Baik, Chul Joon, Lee, Yejin, Hang, Ngo Thanh, Kim, Byung-Gyu, Han, Joo Seok, Jeong, Jae-Hoon, Park, Daechan, Myung, Kyungjae, Lee, Jong-Soo
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2019
Assuntos:
Genome Integrity, Repair and Replication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6753481/
https://ncbi.nlm.nih.gov/pubmed/31340001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz639
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