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Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair
In G(0) and G(1), DNA double strand breaks are repaired by nonhomologous end joining, whereas in S and G(2), they are also repaired by homologous recombination. The human CtIP protein controls double strand break (DSB) resection, an event that occurs effectively only in S/G(2) and that promotes homo...
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| Hauptverfasser: | , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666608/ https://ncbi.nlm.nih.gov/pubmed/19202191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808906200 |
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