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DNA Polymerase β Substrate Specificity: SIDE CHAIN MODULATION OF THE “A-RULE”
Apurinic/apyrimidinic (AP) sites are continuously generated in genomic DNA. Left unrepaired, AP sites represent noninstructional premutagenic lesions that are impediments to DNA synthesis. When DNA polymerases encounter an AP site, they generally insert dAMP. This preferential insertion is referred...
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| 主要な著者: | , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Biochemistry and Molecular Biology
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2797239/ https://ncbi.nlm.nih.gov/pubmed/19759017 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.029843 |
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