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Energy analysis of chemistry for correct insertion by DNA polymerase β
X-ray crystallographic structures of human DNA polymerase β with nonhydrolyzable analogs containing all atoms in the active site required for catalysis provide a secure starting point for a theoretical analysis (quantum mechanics/molecular mechanics) of the mechanism of chemistry without biasing of...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1569157/ https://ncbi.nlm.nih.gov/pubmed/16938895 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606006103 |
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