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Energy analysis of chemistry for correct insertion by DNA polymerase β

X-ray crystallographic structures of human DNA polymerase β with nonhydrolyzable analogs containing all atoms in the active site required for catalysis provide a secure starting point for a theoretical analysis (quantum mechanics/molecular mechanics) of the mechanism of chemistry without biasing of...

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Detalhes bibliográficos
Principais autores: Lin, Ping, Pedersen, Lars C., Batra, Vinod K., Beard, William A., Wilson, Samuel H., Pedersen, Lee G.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1569157/
https://ncbi.nlm.nih.gov/pubmed/16938895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0606006103
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