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DNA polymerase β nucleotide-stabilized template misalignment fidelity depends on local sequence context

DNA polymerase β has two DNA-binding domains that interact with the opposite sides of short DNA gaps. These domains contribute two activities that modify the 5′ and 3′ margins of gapped DNA during base excision repair. DNA gaps greater than 1 nucleotide (nt) pose an architectural and logistical prob...

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Vydáno v:J Biol Chem
Hlavní autoři: Howard, Michael J., Cavanaugh, Nisha A., Batra, Vinod K., Shock, David D., Beard, William A., Wilson, Samuel H.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2020
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956524/
https://ncbi.nlm.nih.gov/pubmed/31801827
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010594
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