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DNA polymerase β nucleotide-stabilized template misalignment fidelity depends on local sequence context
DNA polymerase β has two DNA-binding domains that interact with the opposite sides of short DNA gaps. These domains contribute two activities that modify the 5′ and 3′ margins of gapped DNA during base excision repair. DNA gaps greater than 1 nucleotide (nt) pose an architectural and logistical prob...
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| Gepubliceerd in: | J Biol Chem |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Biochemistry and Molecular Biology
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6956524/ https://ncbi.nlm.nih.gov/pubmed/31801827 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.010594 |
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