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Regulation of Hsp90 client proteins by a Cullin5-RING E3 ubiquitin ligase

We report a link between Cullin5 (Cul5) E3 ubiquitin ligase and the heat shock protein 90 (Hsp90) chaperone complex. Hsp90 participates in the folding of its client proteins into their functional conformation. Many Hsp90 clients have been reported to be aberrantly expressed in a number of cancers. W...

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מידע ביבליוגרפי
Main Authors: Ehrlich, Elana S., Wang, Tao, Luo, Kun, Xiao, Zuoxiang, Niewiadomska, Anna Maria, Martinez, Tara, Xu, Wanping, Neckers, Len, Yu, Xiao-Fang
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2009
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2787120/
https://ncbi.nlm.nih.gov/pubmed/19933325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0810571106
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