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Clients Place Unique Functional Constraints on Hsp90

Hsp90 is required for activation and stabilization of numerous client proteins, yet the functional requirements of individual clients remain poorly understood. Utilizing yeast growth assays and mutational analysis, Mishra and colleagues explore the constraints placed on Hsp90 by distinct clients and...

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Bibliografische gegevens
Gepubliceerd in:Trends Biochem Sci
Hoofdauteurs: Zuehlke, Abbey D., Neckers, Len
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4930374/
https://ncbi.nlm.nih.gov/pubmed/27297784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2016.05.011
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