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Macrophages Create an Acidic Extracellular Hydrolytic Compartment to Digest Aggregated Lipoproteins

A critical event in atherogenesis is the interaction of macrophages with subendothelial lipoproteins. Although most studies model this interaction by incubating macrophages with monomeric lipoproteins, macrophages in vivo encounter lipoproteins that are aggregated. The physical features of the lipop...

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Détails bibliographiques
Auteurs principaux: Haka, Abigail S., Grosheva, Inna, Chiang, Ethan, Buxbaum, Adina R., Baird, Barbara A., Pierini, Lynda M., Maxfield, Frederick R.
Format: Artigo
Langue:Inglês
Publié: The American Society for Cell Biology 2009
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2785736/
https://ncbi.nlm.nih.gov/pubmed/19812252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E09-07-0559
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