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Mechanism for CCC DNA Synthesis in Hepadnaviruses

Hepadnavirus replication requires the synthesis of a covalently closed circular (CCC) DNA from the relaxed circular (RC) viral genome by an unknown mechanism. CCC DNA formation could require enzymatic activities of the viral reverse transcriptase (RT), or cellular DNA repair enzymes, or both. Physic...

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Detalhes bibliográficos
Main Authors: Sohn, Ji A., Litwin, Samuel, Seeger, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2778999/
https://ncbi.nlm.nih.gov/pubmed/19956651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008093
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