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Hepadnavirus Genome Replication and Persistence

Hallmarks of the hepadnavirus replication cycle are the formation of covalently closed circular DNA (cccDNA) and the reverse transcription of a pregenomic RNA (pgRNA) in core particles leading to synthesis of the relaxed circular DNA (rcDNA) genome. cccDNA, the template for viral RNA transcription,...

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Detalles Bibliográficos
Publicado en:Cold Spring Harb Perspect Med
Main Authors: Hu, Jianming, Seeger, Christoph
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4484952/
https://ncbi.nlm.nih.gov/pubmed/26134841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a021386
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