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Characterization of the Host Factors Required for Hepadnavirus Covalently Closed Circular (ccc) DNA Formation

Synthesis of the covalently closed circular (ccc) DNA is a critical, but not well-understood step in the life cycle of hepadnaviruses. Our previous studies favor a model that removal of genome-linked viral DNA polymerase occurs in the cytoplasm and the resulting deproteinized relaxed circular DNA (D...

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Detalhes bibliográficos
Main Authors: Guo, Haitao, Xu, Chunxiao, Zhou, Tianlun, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3418247/
https://ncbi.nlm.nih.gov/pubmed/22912842
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043270
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