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Identification of an Intermediate in Hepatitis B Virus Covalently Closed Circular (CCC) DNA Formation and Sensitive and Selective CCC DNA Detection

Hepatitis B virus (HBV) covalently closed circular (CCC) DNA functions as the only viral template capable of coding for all the viral RNA species and is thus essential to initiate and sustain viral replication. CCC DNA is converted, in a multistep and ill-understood process, from a relaxed circular...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Luo, Jun, Cui, Xiuji, Gao, Lu, Hu, Jianming
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553186/
https://ncbi.nlm.nih.gov/pubmed/28637752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00539-17
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