Identification of an Intermediate in Hepatitis B Virus Covalently Closed Circular (CCC) DNA Formation and Sensitive and Selective CCC DNA Detection

Hepatitis B virus (HBV) covalently closed circular (CCC) DNA functions as the only viral template capable of coding for all the viral RNA species and is thus essential to initiate and sustain viral replication. CCC DNA is converted, in a multistep and ill-understood process, from a relaxed circular...

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Vydáno v:J Virol
Hlavní autoři: Luo, Jun, Cui, Xiuji, Gao, Lu, Hu, Jianming
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2017
Témata:
Genome Replication and Regulation of Viral Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553186/
https://ncbi.nlm.nih.gov/pubmed/28637752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00539-17
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