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Characterization of the Intracellular Deproteinized Relaxed Circular DNA of Hepatitis B Virus: an Intermediate of Covalently Closed Circular DNA Formation

Covalently closed circular DNA (cccDNA) of hepatitis B virus (HBV) is formed by conversion of capsid-associated relaxed circular DNA (rcDNA) via unknown mechanisms and exists in the nucleus of the infected hepatocyte as a minichromosome that serves as the transcription template for viral RNAs. To st...

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Detalhes bibliográficos
Main Authors: Guo, Haitao, Jiang, Dong, Zhou, Tianlun, Cuconati, Andrea, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2169032/
https://ncbi.nlm.nih.gov/pubmed/17804499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01123-07
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