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Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses

Removal of genome-bound viral DNA polymerase ought to be an essential step in the formation of hepadnavirus covalently closed circular DNA (cccDNA). We previously demonstrated that deproteinized (DP) relaxed circular DNA (rcDNA) of hepatitis B virus (HBV) existed in both the cytoplasm and nuclei of...

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Detalhes bibliográficos
Main Authors: Guo, Haitao, Mao, Richeng, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798433/
https://ncbi.nlm.nih.gov/pubmed/19864387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01921-09
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