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Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses

Removal of genome-bound viral DNA polymerase ought to be an essential step in the formation of hepadnavirus covalently closed circular DNA (cccDNA). We previously demonstrated that deproteinized (DP) relaxed circular DNA (rcDNA) of hepatitis B virus (HBV) existed in both the cytoplasm and nuclei of...

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Detalles Bibliográficos
Main Authors: Guo, Haitao, Mao, Richeng, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798433/
https://ncbi.nlm.nih.gov/pubmed/19864387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01921-09
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