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Production and Function of the Cytoplasmic Deproteinized Relaxed Circular DNA of Hepadnaviruses

Removal of genome-bound viral DNA polymerase ought to be an essential step in the formation of hepadnavirus covalently closed circular DNA (cccDNA). We previously demonstrated that deproteinized (DP) relaxed circular DNA (rcDNA) of hepatitis B virus (HBV) existed in both the cytoplasm and nuclei of...

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Autores principales: Guo, Haitao, Mao, Richeng, Block, Timothy M., Guo, Ju-Tao
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology (ASM) 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2798433/
https://ncbi.nlm.nih.gov/pubmed/19864387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01921-09
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