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Cutting Edge: TCR Revision Affects Predominantly Foxp3(−) Cells and Skews Them toward the Th17 Lineage
CD4(+) T cells respond to peripheral endogenous superantigen stimulation by undergoing deletion or TCR revision. The latter involves RAG re-expression, TCR gene rearrangement, and expression of a novel TCR. TCR-revised T cells are functional and express a diverse TCR repertoire. Because TCR revision...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2776039/ https://ncbi.nlm.nih.gov/pubmed/17947636 |
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