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TCR revision generates functional CD4(+) T cells
CD4(+)Vβ5(+) peripheral T cells in B6 mice respond to encounter with a peripherally-expressed endogenous superantigen by undergoing either deletion or TCR revision. In this latter process, cells lose surface Vβ5 expression and undergo RAG-dependent rearrangement of endogenous TCRβ genes, driving sur...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2010
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3233755/ https://ncbi.nlm.nih.gov/pubmed/20971922 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002696 |
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