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Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision

Peripheral CD4(+)Vβ5(+) T cells are tolerized to an endogenous mouse mammary tumor virus superantigen either by deletion or TCR revision. Through TCR revision, RAG reexpression mediates extrathymic TCRβ rearrangement and results in a population of post-revision CD4(+)Vβ5(−) T cells expressing revise...

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Detalhes bibliográficos
Main Authors: Hale, J. Scott, Nelson, Lisa T., Simmons, Kalynn B., Fink, Pamela J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3233758/
https://ncbi.nlm.nih.gov/pubmed/21148799
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1002933
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