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Rag Deletion in Peripheral T Cells Blocks TCR Revision
Mature CD4(+)Vβ5(+) T cells that recognize a peripherally expressed endogenous superantigen are tolerized either by deletion or T cell receptor (TCR) revision. In Vβ5 transgenic mice, this latter tolerance pathway results in the appearance of CD4(+)Vβ5(−)TCRβ(+) T cells, coinciding with Rag1, Rag2,...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2929250/ https://ncbi.nlm.nih.gov/pubmed/20435935 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000876 |
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