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Inflammation and TCR signal strength determine the breadth of the T cell response in a bim-dependent manner
Generating a diverse T-cell memory population through vaccination is a promising strategy to overcome pathogen epitope variability and tolerance to tumor antigens. The effector and memory pool becomes broad in TCR diversity by recruiting high and low affinity T-cells. We wanted to determine which fa...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3903384/ https://ncbi.nlm.nih.gov/pubmed/24273000 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1302289 |
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