Bystander-activated memory CD8 T cells control early pathogen load in an innate-like, NKG2D-dependent manner

During an infection the antigen non-specific memory CD8 T cell compartment is not simply an inert pool of cells, but becomes activated and cytotoxic. It is unknown how these cells contribute to the clearance of an infection. We measured the strength of T-cell receptor (TCR) signals that bystander ac...

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Bibliographic Details
Main Authors: Chu, Talyn, Tyznik, Aaron J., Roepke, Sarah, Berkley, Amy M., Woodward-Davis, Amanda, Pattacini, Laura, Bevan, Michael J., Zehn, Dietmar, Prlic, Martin
Format: Artigo
Language:Inglês
Published: 2013
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3628815/
https://ncbi.nlm.nih.gov/pubmed/23523350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.02.020
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