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Cutting Edge: TCR Revision Affects Predominantly Foxp3(−) Cells and Skews Them toward the Th17 Lineage

CD4(+) T cells respond to peripheral endogenous superantigen stimulation by undergoing deletion or TCR revision. The latter involves RAG re-expression, TCR gene rearrangement, and expression of a novel TCR. TCR-revised T cells are functional and express a diverse TCR repertoire. Because TCR revision...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zehn, Dietmar, Bevan, Michael J., Fink, Pamela J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2007
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2776039/
https://ncbi.nlm.nih.gov/pubmed/17947636
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