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Single-molecule denaturation and degradation of proteins by the AAA+ ClpXP protease

ClpXP is an ATP-fueled molecular machine that unfolds and degrades target proteins. ClpX, an AAA+ enzyme, recognizes specific proteins, and then uses cycles of ATP hydrolysis to denature any native structure and to translocate the unfolded polypeptide into ClpP for degradation. Here, we develop and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Shin, Yongdae, Davis, Joseph H., Brau, Ricardo R., Martin, Andreas, Kenniston, Jon A., Baker, Tania A., Sauer, Robert T., Lang, Matthew J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2009
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2773733/
https://ncbi.nlm.nih.gov/pubmed/19892734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910484106
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