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Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response
ATM and ATR protein kinases play a crucial role in cellular DNA damage responses. The inhibition of ATM and ATR can lead to the abolition of the function of cell cycle checkpoints. In this regard, it is expected that checkpoint inhibitors can serve as sensitizing agents for anti-cancer chemo/radioth...
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| Główni autorzy: | , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2761266/ https://ncbi.nlm.nih.gov/pubmed/19625493 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp593 |
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