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Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1
Mammalian cryptochromes (Crys) are essential circadian clock factors implicated in diverse clock-independent physiological functions, including DNA damage responses. Here we show that Cry1 modulates the ATR-mediated DNA damage checkpoint (DDC) response by interacting with Timeless (Tim) in a time-of...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
Oxford University Press
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3985666/ https://ncbi.nlm.nih.gov/pubmed/24489120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku094 |
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