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Modulation of ATR-mediated DNA damage checkpoint response by cryptochrome 1

Mammalian cryptochromes (Crys) are essential circadian clock factors implicated in diverse clock-independent physiological functions, including DNA damage responses. Here we show that Cry1 modulates the ATR-mediated DNA damage checkpoint (DDC) response by interacting with Timeless (Tim) in a time-of...

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Bibliografiske detaljer
Main Authors: Kang, Tae-Hong, Leem, Sun-Hee
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3985666/
https://ncbi.nlm.nih.gov/pubmed/24489120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gku094
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