Chargement en cours...

A kinetochore-based ATM/ATR-independent DNA damage checkpoint maintains genomic integrity in trypanosomes

DNA damage-induced cell cycle checkpoints serve as surveillance mechanisms to maintain genomic stability, and are regulated by ATM/ATR-mediated signaling pathways that are conserved from yeast to humans. Trypanosoma brucei, an early divergent microbial eukaryote, lacks key components of the conventi...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Nucleic Acids Res
Auteurs principaux: Zhou, Qing, Pham, Kieu T M, Hu, Huiqing, Kurasawa, Yasuhiro, Li, Ziyin
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6736141/
https://ncbi.nlm.nih.gov/pubmed/31147720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkz476
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!