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WWOX modulates the ATR-mediated DNA damage checkpoint response
For many decades genomic instability is considered one of the hallmarks of cancer. Role of the tumor suppressor WWOX (WW domain-containing oxidoreductase) in DNA damage response upon double strand breaks has been recently revealed. Here we demonstrate unforeseen functions for WWOX upon DNA single st...
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| Veröffentlicht in: | Oncotarget |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Impact Journals LLC
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4826209/ https://ncbi.nlm.nih.gov/pubmed/26675548 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6571 |
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