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WWOX guards genome stability by activating ATM
Common fragile sites (CFSs) tend to break upon replication stress and have been suggested to be “hot spots” for genomic instability. Recent evidence, however, implies that in the wake of DNA damage, WW domain-containing oxidoreductase (WWOX, the gene product of the FRA16D fragile site), associates w...
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| 發表在: | Mol Cell Oncol |
|---|---|
| Main Authors: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Taylor & Francis
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4905350/ https://ncbi.nlm.nih.gov/pubmed/27308504 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2015.1008288 |
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