Inhibition of ATR protein kinase activity by schisandrin B in DNA damage response

ATM and ATR protein kinases play a crucial role in cellular DNA damage responses. The inhibition of ATM and ATR can lead to the abolition of the function of cell cycle checkpoints. In this regard, it is expected that checkpoint inhibitors can serve as sensitizing agents for anti-cancer chemo/radioth...

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Bibliografski detalji
Glavni autori: Nishida, Hiroshi, Tatewaki, Naoto, Nakajima, Yuki, Magara, Taku, Ko, Kam Ming, Hamamori, Yasuo, Konishi, Tetsuya
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2009
Teme:
Genome Integrity, Repair and Replication
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2761266/
https://ncbi.nlm.nih.gov/pubmed/19625493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp593
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