A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

Autophagy-essential proteins are the molecular basis of protective or destructive autophagy machinery. However, little is known about the signaling mechanisms governing these proteins and the opposing consequences of autophagy in mammals. Here we report that a non-canonical MEK/ERK module, which is...

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Bibliografiske detaljer
Main Authors: Wang, Jianrong, Whiteman, Mary W., Lian, Huiqin, Wang, Guangxin, Singh, Amit, Huang, Dongyang, Denmark, Ted
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2009
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755866/
https://ncbi.nlm.nih.gov/pubmed/19520853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026013
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