A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

Autophagy-essential proteins are the molecular basis of protective or destructive autophagy machinery. However, little is known about the signaling mechanisms governing these proteins and the opposing consequences of autophagy in mammals. Here we report that a non-canonical MEK/ERK module, which is...

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Detalles Bibliográficos
Main Authors: Wang, Jianrong, Whiteman, Mary W., Lian, Huiqin, Wang, Guangxin, Singh, Amit, Huang, Dongyang, Denmark, Ted
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Mechanisms of Signal Transduction
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755866/
https://ncbi.nlm.nih.gov/pubmed/19520853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026013
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