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MyD88 and Trif Target Beclin 1 to Trigger Autophagy in Macrophages
The Toll-like receptors (TLR) play an instructive role in innate and adaptive immunity by recognizing specific molecular patterns from pathogens. Autophagy removes intracellular pathogens and participates in antigen presentation. Here, we demonstrate that not only TLR4, but also other TLR family mem...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2586260/ https://ncbi.nlm.nih.gov/pubmed/18772134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804478200 |
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