A Non-canonical MEK/ERK Signaling Pathway Regulates Autophagy via Regulating Beclin 1

Autophagy-essential proteins are the molecular basis of protective or destructive autophagy machinery. However, little is known about the signaling mechanisms governing these proteins and the opposing consequences of autophagy in mammals. Here we report that a non-canonical MEK/ERK module, which is...

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Détails bibliographiques
Auteurs principaux: Wang, Jianrong, Whiteman, Mary W., Lian, Huiqin, Wang, Guangxin, Singh, Amit, Huang, Dongyang, Denmark, Ted
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2009
Sujets:
Mechanisms of Signal Transduction
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755866/
https://ncbi.nlm.nih.gov/pubmed/19520853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.026013
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