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Divergent regulation of GIRK1 and GIRK2 subunits of the neuronal G protein gated K(+) channel by Gα(i)(GDP) and Gβγ
G protein activated K(+) channels (GIRK, Kir3) are switched on by direct binding of Gβγ following activation of G(i/o) proteins via G protein-coupled receptors (GPCRs). Although Gα(i) subunits do not activate GIRKs, they interact with the channels and regulate the gating pattern of the neuronal hete...
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| Glavni autori: | , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Blackwell Science Inc
2009
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2742276/ https://ncbi.nlm.nih.gov/pubmed/19470775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2009.173229 |
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