Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells

Palindromic regions are unstable and susceptible to deletion in prokaryotes and eukaryotes possibly due to stalled or slow replication. In the human genome, they also appear to become partially or completely deleted, while two palindromic AT-rich repeats (PATRR) contribute to known recurrent constit...

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Autori principali: Kurahashi, Hiroki, Inagaki, Hidehito, Kato, Takema, Hosoba, Eriko, Kogo, Hiroshi, Ohye, Tamae, Tsutsumi, Makiko, Bolor, Hasbaira, Tong, Maoqing, Emanuel, Beverly S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729664/
https://ncbi.nlm.nih.gov/pubmed/19520744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp279
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