Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells

Palindromic regions are unstable and susceptible to deletion in prokaryotes and eukaryotes possibly due to stalled or slow replication. In the human genome, they also appear to become partially or completely deleted, while two palindromic AT-rich repeats (PATRR) contribute to known recurrent constit...

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Bibliographische Detailangaben
Hauptverfasser: Kurahashi, Hiroki, Inagaki, Hidehito, Kato, Takema, Hosoba, Eriko, Kogo, Hiroshi, Ohye, Tamae, Tsutsumi, Makiko, Bolor, Hasbaira, Tong, Maoqing, Emanuel, Beverly S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2009
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729664/
https://ncbi.nlm.nih.gov/pubmed/19520744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp279
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