Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells

Palindromic regions are unstable and susceptible to deletion in prokaryotes and eukaryotes possibly due to stalled or slow replication. In the human genome, they also appear to become partially or completely deleted, while two palindromic AT-rich repeats (PATRR) contribute to known recurrent constit...

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Autors principals: Kurahashi, Hiroki, Inagaki, Hidehito, Kato, Takema, Hosoba, Eriko, Kogo, Hiroshi, Ohye, Tamae, Tsutsumi, Makiko, Bolor, Hasbaira, Tong, Maoqing, Emanuel, Beverly S.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2009
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2729664/
https://ncbi.nlm.nih.gov/pubmed/19520744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp279
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