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Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells
Palindromic regions are unstable and susceptible to deletion in prokaryotes and eukaryotes possibly due to stalled or slow replication. In the human genome, they also appear to become partially or completely deleted, while two palindromic AT-rich repeats (PATRR) contribute to known recurrent constit...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729664/ https://ncbi.nlm.nih.gov/pubmed/19520744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp279 |
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