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Impaired DNA replication prompts deletions within palindromic sequences, but does not induce translocations in human cells
Palindromic regions are unstable and susceptible to deletion in prokaryotes and eukaryotes possibly due to stalled or slow replication. In the human genome, they also appear to become partially or completely deleted, while two palindromic AT-rich repeats (PATRR) contribute to known recurrent constit...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2729664/ https://ncbi.nlm.nih.gov/pubmed/19520744 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp279 |
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