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Transition state analogues in quorum sensing and SAM recycling
Transition state structures can be derived from kinetic isotope effects and computational chemistry. Molecular electrostatic potential maps of transition states serve as blueprints to guide synthesis of transition state analogue inhibitors of target enzymes. 5’-Methylthioadenosine phosphorylase (MTA...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2725438/ https://ncbi.nlm.nih.gov/pubmed/18776260 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nass/nrn038 |
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