Distinct thresholds govern Myc’s biological output in vivo

Deregulated Myc triggers a variety of intrinsic tumor suppressor programs that serve to restrain Myc’s oncogenic potential. Since Myc activity is also required for normal cell proliferation, activation of intrinsic tumor suppression must be triggered only when Myc signaling is oncogenic. However, ho...

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Bibliografiske detaljer
Main Authors: Daniel, J. Murphy, Junttila, Melissa R., Pouyet, Laurent, Karnezis, Anthony, Shchors, Ksenya, Bui, Duyen A., Brown-Swigart, Lamorna, Johnson, Leisa, Evan, Gerard. I.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2723751/
https://ncbi.nlm.nih.gov/pubmed/19061836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2008.10.018
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